IEECAS OpenIR  > 黄土与第四纪地质国家重点实验室(2010~)
Modeling micro-particle deposition in human upper respiratory tract under steady inhalation
Huang, JH (Huang, Jianhua)[1]; Zhang, LZ (Zhang, Lianzhong)[1,2]; Yu, SY (Yu, Suyuan)[3]
2011-02-28
Source PublicationPARTICUOLOGY
Volume9Issue:1Pages:39-43
Subtype期刊论文
Abstract

A representative human upper respiratory tract (URT) with idealized oral region and asymmetric tracheabronchial (TB) airway has been modeled, and laminar-to-turbulent airflow for typical inhalation modes as well as micro-particle transport and deposition has been simulated using CFX10.0 software from Ansys Inc. on a personal computer. The asymmetric TB airway could not be replaced by an extended straight tube as outlet of the oral region while investigating the tracheal airflow field and particle deposition. Compared to an idealized oral airway with an extended straight tube, several differences could be noted: (i) The laryngeal jet extends further down the trachea and inclines towards the anterior wall; (ii) the turbulence level in trachea is less and decays more quickly; (iii) three recirculation zones are visible with intense adverse current after the glottis; (iv) deposition of small particles in trachea is reduced due to lower turbulence. Refined unstructured mesh with densified boundary layer mesh could be a proper substitute for the structured mesh in the human URT model with asymmetric TB airway. Based on the refined unstructured mesh, the physiological structure of uvula in the soft palate is properly simulated in the present human URT model.

KeywordHuman upper airway model Asymmetric tracheobronchial (TB) airway Particle deposition Computational fluid-particle dynamic simulations
DOI10.1016/j.partic.2010.04.003
Indexed BySCI
Language英语
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ieecas.cn/handle/361006/10299
Collection黄土与第四纪地质国家重点实验室(2010~)
Corresponding AuthorZhang, LZ (Zhang, Lianzhong)[1,2]
Affiliation1.School of Physics, Nankai University, Tianjin 300071, China;
2.State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China;
3.Institute of Nuclear Energy and New Energy Technology, Tsinghua University, Beijing 100084, China
Recommended Citation
GB/T 7714
Huang, JH ,Zhang, LZ ,Yu, SY . Modeling micro-particle deposition in human upper respiratory tract under steady inhalation[J]. PARTICUOLOGY,2011,9(1):39-43.
APA Huang, JH ,Zhang, LZ ,&Yu, SY .(2011).Modeling micro-particle deposition in human upper respiratory tract under steady inhalation.PARTICUOLOGY,9(1),39-43.
MLA Huang, JH ,et al."Modeling micro-particle deposition in human upper respiratory tract under steady inhalation".PARTICUOLOGY 9.1(2011):39-43.
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