IEECAS OpenIR  > 黄土与第四纪地质国家重点实验室(2010~)
Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study
Chuang, Hsiao-Chi1,2,3; Ho, Kin-Fai4,5,6; Lin, Lian-Yu7; Chang, Ta-Yuan8; Hong, Gui-Bing9; Ma, Chi-Ming10; Liu, I-Jung11; Chuang, Kai-Jen12
AbstractThe association of short-term air pollution filtration with cardiovascular health has been documented. However, the effect of long-term indoor air conditioner filtration on the association between air pollution and cardiovascular health is still unclear. We recruited 200 homemakers from Taipei and randomly assigned 100 of them to air filtration or control intervention; six home visits were conducted per year from 2013 to 2014. The participants under air filtration intervention during 2013 were reassigned to control intervention in 2014. The air pollution measurements consisted of particulate matter less than or equal to 2.5 mu m in diameter (PM2.5) and total volatile organic compounds (VOCs); blood pressure was monitored for each participant during each visit. The following morning, blood samples were collected after air pollution monitoring. The blood samples were used to analyze biological markers, including high sensitivity-C-reactive protein (hs-CRP), 8-hydroxy-2'-deoxyguanosine (8-OHdG) and fibrinogen. Household information, including cleaning, cooking, and air conditioning, was collected by a questionnaire. effects models were used to investigate the associations among air pollution measurements, blood pressure and biological markers. The results showed that increased levels of PM2.5 and total VOCs were associated with increased hs-CRP, 8-OHdG and blood pressure. The health variables were higher among participants in the control intervention phase than among those in the air filtration intervention phase. We concluded that air pollution exposure was associated with systemic inflammation, oxidative stress and elevated blood pressure. The long-term filtration of air pollution with an air conditioner filter was associated with cardiovascular health of adults.
KeywordAir Pollution Indoor Air Filtration Inflammation Blood Pressure Epidemiology
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI
WOS Research AreaEnvironmental Sciences & Ecology
WOS SubjectEnvironmental Sciences
WOS IDWOS:000406175300010
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Document Type期刊论文
Affiliation1.Taipei Med Univ, Coll Med, Sch Resp Therapy, Taipei, Taiwan
2.Taipei Med Univ, Shuang Ho Hosp, Dept Internal Med, Div Pulm Med, New Taipei, Taiwan
3.Taipei Med Univ, Coll Med, Sch Med, Dept Internal Med, Taipei, Taiwan
4.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China
5.Chinese Acad Sci, Inst Earth Environm, SKLLQG, Key Lab Aerosol Chem & Phys, Xian 710075, Peoples R China
6.Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen Municipal Key Lab Hlth Risk Anal, Shenzhen, Peoples R China
7.Natl Taiwan Univ Hosp, Dept Internal Med, Div Cardiol, Taipei, Taiwan
8.China Med Univ, Coll Publ Hlth, Dept Occupat Safety & Hlth, Taichung, Taiwan
9.Natl Taipei Univ Technol, Dept Chem Engn & Biotechnol, Taipei, Taiwan
10.St Marys Jr Coll Med Nursing & Management, Dept Cosmet Applicat & Management, Sanxing Township, Yilan County, Taiwan
11.Cardinal Tien Coll Healthcare & Management, Dept Nursing, New Taipei, Taiwan
12.Taipei Med Univ, Coll Med, Sch Med, Dept Publ Hlth, Taipei, Taiwan
Recommended Citation
GB/T 7714
Chuang, Hsiao-Chi,Ho, Kin-Fai,Lin, Lian-Yu,et al. Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study[J]. ENVIRONMENT INTERNATIONAL,2017,106(2017):91-96.
APA Chuang, Hsiao-Chi.,Ho, Kin-Fai.,Lin, Lian-Yu.,Chang, Ta-Yuan.,Hong, Gui-Bing.,...&Chuang, Kai-Jen.(2017).Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study.ENVIRONMENT INTERNATIONAL,106(2017),91-96.
MLA Chuang, Hsiao-Chi,et al."Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study".ENVIRONMENT INTERNATIONAL 106.2017(2017):91-96.
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