Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong

doi:10.1016/j.scitotenv.2020.140501

IEECAS OpenIR > 粉尘与环境研究室

	Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong
	Chen, Xiao-Cui 1,8,10; Cao, Jun-Ji 2; Ward, Tony J.3; Tian, Lin-Wei 4; Ning, Zhi 5; Gali, Nirmal Kumar 5; Aquilina, Noel J.6; Yim, Steve Hung-Lam 1,9; Qu, Linli 11; Ho, Kin-Fai 1,7
通讯作者	Ho, Kin-Fai(kfho@cuhk.edu.hk)
	2020-11-10
发表期刊	SCIENCE OF THE TOTAL ENVIRONMENT
ISSN	0048-9697
卷号	742 页码:12
摘要	Epidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016-2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 mu g/m(3) on the bus and 5.5 to 8.7 mu g/m(3) in MTR cabin (p < .05). PM2.5 mass andmajor chemical constituents (including organic carbon (OC), elemental carbon (EC), andmetals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variationswere observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00-11:00) and evening rush hours (17:30-20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, alongwith higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health. (C) 2020 Elsevier B.V. All rights reserved.
关键词	Commuter exposure Black carbon Transition metals Cytotoxicity Reactive oxygen species (ROS)
DOI	10.1016/j.scitotenv.2020.140501
关键词[WOS]	PARTICULATE AIR-POLLUTION ; PERSONAL EXPOSURE ; OXIDATIVE STRESS ; TRANSPORT MICROENVIRONMENTS ; ELEMENTAL COMPOSITION ; MATTER PM ; COARSE ; ASSOCIATIONS ; VARIABILITY ; BIOMARKERS
收录类别	SCI ; SCI
语种	英语
资助项目	Research Grants Council of The Hong Kong Special Administrative Region of China[14202817] ; Research Grants Council of The Hong Kong Special Administrative Region of China[14212116] ; Research Grants Council of The Hong Kong Special Administrative Region of China[412413]
WOS研究方向	Environmental Sciences & Ecology
项目资助者	Research Grants Council of The Hong Kong Special Administrative Region of China
WOS类目	Environmental Sciences
WOS记录号	WOS:000569416600009
出版者	ELSEVIER
引用统计	被引频次：26[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ieecas.cn/handle/361006/15296
专题	粉尘与环境研究室
通讯作者	Ho, Kin-Fai
作者单位	1.Chinese Univ Hong Kong, Inst Environm Energy & Sustainabil, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Earth Environm, Key Lab Aerosol, SKLLQG, Xian, Peoples R China 3.Univ Montana, Sch Publ & Community Hlth Sci, Missoula, MT 59812 USA 4.Univ Hong Kong, Sch Publ Hlth, Hong Kong, Peoples R China 5.Hong Kong Univ Sci & Technol, Div Environm & Sustainabil, Hong Kong, Peoples R China 6.Univ Malta, Dept Geosci, MSD-2080 Msida, Malta 7.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China 8.Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China 9.Chinese Univ Hong Kong, Dept Geog & Resource Management, Hong Kong, Peoples R China 10.Univ Hong Kong, Hlth High Dens Cities Lab, HKUrbanLab, Hong Kong, Peoples R China 11.Hong Kong Premium Serv & Res Lab, Cheng Sha Wan, Kowloon, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Chen, Xiao-Cui,Cao, Jun-Ji,Ward, Tony J.,et al. Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,742:12.
APA	Chen, Xiao-Cui.,Cao, Jun-Ji.,Ward, Tony J..,Tian, Lin-Wei.,Ning, Zhi.,...&Ho, Kin-Fai.(2020).Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong.SCIENCE OF THE TOTAL ENVIRONMENT,742,12.
MLA	Chen, Xiao-Cui,et al."Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong".SCIENCE OF THE TOTAL ENVIRONMENT 742(2020):12.