| Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong | |
| Chen, Xiao-Cui1,8,10; Cao, Jun-Ji2; Ward, Tony J.3; Tian, Lin-Wei4; Ning, Zhi5; Gali, Nirmal Kumar5; Aquilina, Noel J.6; Yim, Steve Hung-Lam1,9; Qu, Linli11; Ho, Kin-Fai1,7 | |
| Corresponding Author | Ho, Kin-Fai(kfho@cuhk.edu.hk) |
| 2020-11-10 | |
| Source Publication | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| ISSN | 0048-9697 |
| Volume | 742Pages:12 |
| Abstract | Epidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016-2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 mu g/m(3) on the bus and 5.5 to 8.7 mu g/m(3) in MTR cabin (p < .05). PM2.5 mass andmajor chemical constituents (including organic carbon (OC), elemental carbon (EC), andmetals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variationswere observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00-11:00) and evening rush hours (17:30-20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, alongwith higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health. (C) 2020 Elsevier B.V. All rights reserved. |
| Keyword | Commuter exposure Black carbon Transition metals Cytotoxicity Reactive oxygen species (ROS) |
| DOI | 10.1016/j.scitotenv.2020.140501 |
| WOS Keyword | PARTICULATE AIR-POLLUTION ; PERSONAL EXPOSURE ; OXIDATIVE STRESS ; TRANSPORT MICROENVIRONMENTS ; ELEMENTAL COMPOSITION ; MATTER PM ; COARSE ; ASSOCIATIONS ; VARIABILITY ; BIOMARKERS |
| Indexed By | SCI ; SCI |
| Language | 英语 |
| Funding Project | Research Grants Council of The Hong Kong Special Administrative Region of China[14202817] ; Research Grants Council of The Hong Kong Special Administrative Region of China[14212116] ; Research Grants Council of The Hong Kong Special Administrative Region of China[412413] |
| WOS Research Area | Environmental Sciences & Ecology |
| Funding Organization | Research Grants Council of The Hong Kong Special Administrative Region of China |
| WOS Subject | Environmental Sciences |
| WOS ID | WOS:000569416600009 |
| Publisher | ELSEVIER |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ieecas.cn/handle/361006/15296 |
| Collection | 粉尘与环境研究室 |
| Corresponding Author | Ho, Kin-Fai |
| Affiliation | 1.Chinese Univ Hong Kong, Inst Environm Energy & Sustainabil, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Earth Environm, Key Lab Aerosol, SKLLQG, Xian, Peoples R China 3.Univ Montana, Sch Publ & Community Hlth Sci, Missoula, MT 59812 USA 4.Univ Hong Kong, Sch Publ Hlth, Hong Kong, Peoples R China 5.Hong Kong Univ Sci & Technol, Div Environm & Sustainabil, Hong Kong, Peoples R China 6.Univ Malta, Dept Geosci, MSD-2080 Msida, Malta 7.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China 8.Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China 9.Chinese Univ Hong Kong, Dept Geog & Resource Management, Hong Kong, Peoples R China 10.Univ Hong Kong, Hlth High Dens Cities Lab, HKUrbanLab, Hong Kong, Peoples R China 11.Hong Kong Premium Serv & Res Lab, Cheng Sha Wan, Kowloon, Hong Kong, Peoples R China |
| Recommended Citation GB/T 7714 | Chen, Xiao-Cui,Cao, Jun-Ji,Ward, Tony J.,et al. Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,742:12. |
| APA | Chen, Xiao-Cui.,Cao, Jun-Ji.,Ward, Tony J..,Tian, Lin-Wei.,Ning, Zhi.,...&Ho, Kin-Fai.(2020).Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong.SCIENCE OF THE TOTAL ENVIRONMENT,742,12. |
| MLA | Chen, Xiao-Cui,et al."Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong".SCIENCE OF THE TOTAL ENVIRONMENT 742(2020):12. |
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