Surface Characterization of Secondary Organic Aerosols from Ozonolysis of Monoterpene and the Effects of Acute Lung Injury in Mice | |
Niu, Xinyi1; Huang, Yu2,3; Lee, Shuncheng4; Sun, Jian5; Ho, Kin Fai1 | |
通讯作者 | Huang, Yu() ; Ho, Kin Fai(kfho@cuhk.edu.hk) |
2020-07-01 | |
发表期刊 | AEROSOL AND AIR QUALITY RESEARCH |
ISSN | 1680-8584 |
卷号 | 20期号:7页码:1675-1685 |
摘要 | Monoterpene is a biogenic volatile organic compound commonly found in cleaning products and air fresheners. It can react rapidly with indoor oxidants, such as ozone (O-3), to produce secondary organic aerosols (SOAs) in indoor environments, and the reactions are potentially influenced by ammonia (NH3). This study simulated the reactions of O-3 and monoterpene with and without the presence of NH3 in an environmental chamber and investigated the surface characterization (elemental components and carbon states) of the PM2.5 generated by these reactions. We found that the generated particles possessed a higher content of nitrogen-containing organic compounds when NH3 was present. Unsubstituted aromatic carbon and aliphatic carbon were the main carbon structures, exhibited by over 60% of the carbon-containing compounds. Additionally, in the presence of NH3, more amide carbon and carboxylic carbon formed during the reactions. We also examined acute lung injury in mice caused by new particle formation under different reaction conditions. Oxidative stress was observed in the bronchoalveolar lavage fluid of the mice, as evidenced by a decrease in antioxidant enzymes (superoxide dismutase) and antioxidants (glutathione) as well as an increase in malondialdehyde. Moreover, the SOAs generated in the presence of NH3 lowered glutathione levels, indicating a rise in oxidative stress. Hence, fine particles formed by indoor oxidative reactions may trigger acute lung injury in humans, potentially causing further respiratory disease. |
关键词 | Indoor air pollution SOA Oxidative stress Acute lung injury |
DOI | 10.4209/aaqr.2019.12.0628 |
关键词[WOS] | FINE PARTICULATE MATTER ; X-RAY PHOTOELECTRON ; OXIDATIVE STRESS ; CHEMICAL-COMPOSITION ; EPITHELIAL-CELLS ; DNA-DAMAGE ; PARTICLES ; INDOOR ; PM2.5 ; OZONE |
收录类别 | SCI ; SCI |
语种 | 英语 |
WOS研究方向 | Environmental Sciences & Ecology |
WOS类目 | Environmental Sciences |
WOS记录号 | WOS:000548340000019 |
出版者 | TAIWAN ASSOC AEROSOL RES-TAAR |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ieecas.cn/handle/361006/15060 |
专题 | 粉尘与环境研究室 |
通讯作者 | Huang, Yu; Ho, Kin Fai |
作者单位 | 1.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Earth Environm, Key Lab Aerosol Chem & Phys, Xian 710075, Peoples R China 3.Chinese Acad Sci, Inst Earth Environm, State Key Lab Loess & Quaternary Geol SKLLQG, Xian 710061, Peoples R China 4.Hong Kong Polytech Univ, Dept Civil & Environm Engn, Hong Kong, Peoples R China 5.Xi An Jiao Tong Univ, Sch Human Settlements & Civil Engn, Xian 710049, Peoples R China |
推荐引用方式 GB/T 7714 | Niu, Xinyi,Huang, Yu,Lee, Shuncheng,et al. Surface Characterization of Secondary Organic Aerosols from Ozonolysis of Monoterpene and the Effects of Acute Lung Injury in Mice[J]. AEROSOL AND AIR QUALITY RESEARCH,2020,20(7):1675-1685. |
APA | Niu, Xinyi,Huang, Yu,Lee, Shuncheng,Sun, Jian,&Ho, Kin Fai.(2020).Surface Characterization of Secondary Organic Aerosols from Ozonolysis of Monoterpene and the Effects of Acute Lung Injury in Mice.AEROSOL AND AIR QUALITY RESEARCH,20(7),1675-1685. |
MLA | Niu, Xinyi,et al."Surface Characterization of Secondary Organic Aerosols from Ozonolysis of Monoterpene and the Effects of Acute Lung Injury in Mice".AEROSOL AND AIR QUALITY RESEARCH 20.7(2020):1675-1685. |
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