Characteristics and cytotoxicity of indoor fine particulate matter (PM2.5) and PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Hong Kong

doi:10.1007/s11869-019-00762-0

IEECAS OpenIR > 粉尘与环境研究室

	Characteristics and cytotoxicity of indoor fine particulate matter (PM2.5) and PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Hong Kong
	Tong, Xinning 1; Chen, Xiao-Cui 2; Chuang, Hsiao-Chi 3; Cao, Jun-Ji 4,5; Ho, Steven Sai Hang 6; Lui, Ka-Hei 1; Ho, K. F.1
通讯作者	Ho, K. F.(kfho@cuhk.edu.hk)
	2019-10-28
发表期刊	AIR QUALITY ATMOSPHERE AND HEALTH
ISSN	1873-9318
页码	10
摘要	Organic components of fine particles, especially polycyclic aromatic hydrocarbons (PAHs), play an essential role in the toxicity of fine particulate matter (PM2.5). The chemical and bioreactive properties of PM2.5 in indoor environments were investigated from 2014 to 2016 in Hong Kong among 33 residential indoor environments. All analyzed components revealed higher concentrations in winter than in summer, except for organic carbon (OC). High molecular weight PAHs (4-6 rings) contributed higher total PAH compositions than low molecular weight PAHs (2-3 rings). The study results suggested that the major sources of indoor PM2.5 originated from outdoor vehicle emissions, indoor cooking activities, and incense burning. Cytotoxicity tests only revealed significant associations in winter. The cell viability demonstrated strong negative correlations between OC (r = - 0.8, p < 0.05), total PM2.5-bound PAHs (r = - 0.6, p < 0.05), and United States Environmental Protection Agency (US EPA) priority PAHs (r = - 0.7, p < 0.05). Cell lactate dehydrogenase (LDH) and 8-isoprostane were positively associated with OC (r = 0.8, p < 0.05; r = 0.7, p < 0.05), total PM2.5-bound PAH (r = 0.7, p < 0.05; r = 0.7, p < 0.05), and US EPA priority PAH (r = 0.6, p < 0.05; r = 0.5, p = 0.07) concentrations. IL-6 had the only positive association with OC (r = 0.5, p < 0.05). This study focused on indoor PM2.5 levels and the associated cytotoxicity in the absence of environmental tobacco smoke.
关键词	Indoor air PM2 5 Organic carbon PAHs Cytotoxicity
DOI	10.1007/s11869-019-00762-0
关键词[WOS]	AIR-QUALITY ; ORGANIC-COMPOUNDS ; OUTDOOR AIR ; EXPOSURE ; RISK ; DERIVATIVES ; POLLUTION ; TOXICITY ; COOKING ; IMPACT
收录类别	SCI ; SCI
语种	英语
资助项目	Research Grants Council of the Hong Kong SpecialAdministrative Region of China[14212116] ; Ministry of Science and Technology of China[2013FY112700]
WOS研究方向	Environmental Sciences & Ecology
项目资助者	Research Grants Council of the Hong Kong SpecialAdministrative Region of China ; Ministry of Science and Technology of China
WOS类目	Environmental Sciences
WOS记录号	WOS:000492926800001
出版者	SPRINGER
引用统计	被引频次：15[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ieecas.cn/handle/361006/12909
专题	粉尘与环境研究室
通讯作者	Ho, K. F.
作者单位	1.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China 2.Chinese Univ Hong Kong, Inst Environm Energy & Sustainabil, Hong Kong, Peoples R China 3.Taipei Med Univ, Coll Med, Sch Resp Therapy, Taipei, Taiwan 4.Chinese Acad Sci, SKLLQG, Inst Earth Environm, Key Lab Aerosol Chem & Phys, Xian 710075, Shaanxi, Peoples R China 5.Chinese Acad Sci, Inst Earth & Environm, State Key Lab Loess & Quaternary Geol, Xian 710075, Shaanxi, Peoples R China 6.Desert Res Inst, Div Atmospher Sci, Reno, NV USA
推荐引用方式 GB/T 7714	Tong, Xinning,Chen, Xiao-Cui,Chuang, Hsiao-Chi,et al. Characteristics and cytotoxicity of indoor fine particulate matter (PM2.5) and PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Hong Kong[J]. AIR QUALITY ATMOSPHERE AND HEALTH,2019:10.
APA	Tong, Xinning.,Chen, Xiao-Cui.,Chuang, Hsiao-Chi.,Cao, Jun-Ji.,Ho, Steven Sai Hang.,...&Ho, K. F..(2019).Characteristics and cytotoxicity of indoor fine particulate matter (PM2.5) and PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Hong Kong.AIR QUALITY ATMOSPHERE AND HEALTH,10.
MLA	Tong, Xinning,et al."Characteristics and cytotoxicity of indoor fine particulate matter (PM2.5) and PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Hong Kong".AIR QUALITY ATMOSPHERE AND HEALTH (2019):10.