IEECAS OpenIR  > 黄土与第四纪地质国家重点实验室(2010~)
Numerical simulation of micro-particle deposition in a realistic human upper respiratory tract model during transient breathing cycle
Huang, JH (Huang, Jianhua)[1]; Zhang, LZ (Zhang, Lianzhong)[2,3]
2011-08-30
Source PublicationPARTICUOLOGY
Volume9Issue:4(Si)Pages:424-431
Subtype期刊论文
Abstract

An more reliable human upper respiratory tract model that consisted of an oropharynx and four generations of asymmetric tracheo-bronchial (TB) airways has been constructed to investigate the micro-particle deposition pattern and mass distribution in five lobes under steady inspiratory condition in former work by Huang and Zhang (2011). In the present work, transient airflow patterns and particle deposition during both inspiratory and expiratory processes were numerically simulated in the realistic human upper respiratory tract model with 14 cartilaginous rings (CRs) in the tracheal tube. The present model was validated under steady inspiratory flow rates by comparing current results with the theoretical models and published experimental data. The transient deposition fraction was found to strongly depend on breathing flow rate and particle diameter but slightly on turbulence intensity. Particles were mainly distributed in the high axial speed zones and traveled basically following the secondary flow. "Hot spots" of deposition were found in the lower portion of mouth cavity and posterior wall of pharynx/larynx during inspiration, but transferred to upper portion of mouth and interior wall of pharynx/larynx during expiration. The deposition fraction in the trachea during expiration was found to be much higher than that during inspiration because of the stronger secondary flow. (C) 2011 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

KeywordHuman upper respiratory tract Transient breathing cycle Airflow pattern Micro-particle deposition
DOI10.1007/s11434-010-4305-y
Indexed BySCI
Language英语
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ieecas.cn/handle/361006/10331
Collection黄土与第四纪地质国家重点实验室(2010~)
Corresponding AuthorZhang, LZ (Zhang, Lianzhong)[2,3]
Affiliation1.Jiangsu Xuzhou Construction Machinery Research Institute, XCMG Co., Ltd., Xuzhou 221004, China;
2.School of Physics, Nankai University, Tianjin 300071, China;
3.State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China
Recommended Citation
GB/T 7714
Huang, JH ,Zhang, LZ . Numerical simulation of micro-particle deposition in a realistic human upper respiratory tract model during transient breathing cycle[J]. PARTICUOLOGY,2011,9(4(Si)):424-431.
APA Huang, JH ,&Zhang, LZ .(2011).Numerical simulation of micro-particle deposition in a realistic human upper respiratory tract model during transient breathing cycle.PARTICUOLOGY,9(4(Si)),424-431.
MLA Huang, JH ,et al."Numerical simulation of micro-particle deposition in a realistic human upper respiratory tract model during transient breathing cycle".PARTICUOLOGY 9.4(Si)(2011):424-431.
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