IEECAS OpenIR  > 黄土与第四纪地质国家重点实验室(2010~)
Micro-particle deposition and lobar distribution of mass flow in human upper respiratory tract model
Huang,JH (Huang,JianHua)[1]; Zhang,LZ (Zhang,LianZhong)[1,2]
2011-02-28
Source PublicationCHINESE SCIENCE BULLETIN
Volume56Issue:4-5Pages:380-385
Subtype期刊论文
Abstract

A representative human upper respiratory tract model consisting of oropharyngeal and asymmetric tracheobronchial (TB) airways from the trachea (G0) to the main lobar bronchi (G2) was constructed. Laminar-to-turbulent airflow for typical inhalation modes as well as micro-particle transportation, wall deposition and mass flow to lobes was simulated using the CFX10.0 software from Ansys Inc. The numerical particle deposition efficiency of the oropharynx region and two generations (G1 and G2) of TB airways shows great agreement with the experimental data obtained from realistic casts. The particle deposition pattern indicates that inertial impaction is the primary mechanism in the human upper airway, and turbulence dispersion performs crescent influence especially for small particles. The initial positions of particles with different fates are confined to specifically concentrated zones. The particle mass distributions of five lobes are close to airflow distributions. The upper lobes receive fewer particles than lower lobes and the right middle lobe receives the least.

Keywordupper respiratory tract asymmetric tracheobronchial airways transportation and deposition lobar differences computational fluid dynamics simulation
DOI10.1007/s11434-010-4305-y
Indexed BySCI
Language英语
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ieecas.cn/handle/361006/10296
Collection黄土与第四纪地质国家重点实验室(2010~)
Corresponding AuthorZhang,LZ (Zhang,LianZhong)[1,2]
Affiliation1.School of Physics, Nankai University, Tianjin 300071, China;
2.State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China
Recommended Citation
GB/T 7714
Huang,JH ,Zhang,LZ . Micro-particle deposition and lobar distribution of mass flow in human upper respiratory tract model[J]. CHINESE SCIENCE BULLETIN,2011,56(4-5):380-385.
APA Huang,JH ,&Zhang,LZ .(2011).Micro-particle deposition and lobar distribution of mass flow in human upper respiratory tract model.CHINESE SCIENCE BULLETIN,56(4-5),380-385.
MLA Huang,JH ,et al."Micro-particle deposition and lobar distribution of mass flow in human upper respiratory tract model".CHINESE SCIENCE BULLETIN 56.4-5(2011):380-385.
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